cryo-electron microscopy 

The recent “resolution revolution” cryo-electron microscopy (cryo-EM; Nobel Prize 2017 to Henderson, Frank & Dubochet), finally enables it to reach atomic resolution on biological samples. This has produced an explosion of novel structural information and high-impact results. The CRBS and its umbrella-associated facility, the McGill Facility for Electron Microscopy (FEMR) has the cutting-edge infrastructure and expertise for atomic resolution single particle EM and detailed cellular cryo-electron tomography.

 

The CRBS home floor of the Bellini Building houses all preparatory equipment required for single particle (Vitrobot, carbon coater and glow discharger), while the FEMR facility in Strathcona houses preparation equipment and the most advanced microscopes, including a Titan Krios with K3 direct electron detector.

To access the cryo-electron microscopy prep hub, please inquire here: